Protein Modification Reagents
eMolecules Hydroxy-PEG3-t-butyl ester | Broadpharm | 186020-66-6 | MFCD03791106 | 278.345 | C13H26O6 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCO | 5g | 112541344
Hydroxy-PEG3-t-butyl ester | Broadpharm | 186020-66-6 | MFCD03791106 | 278.345 | C13H26O6 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCO | 5g | 112541344
eMolecules BDP FL-PEG4-amine TFA salt | 2183473-14-3 | | 100mg
Broadpharm | BDP FL-PEG4-amine TFA salt | 100mg | 462125625 | BP-23885 | 98.000 | 2183473-14-3 | | 510.390 | C24H37BF2N4O5
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Medchemexpress LLC Biotin-PEG4-alkyne | 1458576-00-5 | 99.7% | C21H35N3O6S | 50 MG
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess Azide groups. This product is intended for research use only and is not sold to patients.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Supports selective degradation of target proteins via the ubiquitin-proteasome system
Medchemexpress LLC Mal-PEG4-NHS ester | 1325208-25-0 | MFCD20230464 | 99.4% | 442.42 g/mol | C19H26N2O10 | 100 MG
Mal-PEG4-NHS ester is a heterobifunctional PEG linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester; it is used for conjugating thiol-containing molecules to amines and for ADC and bioconjugation applications.
- Maleimide reacts with thiols for site-specific conjugation.
- NHS ester reacts with primary amines under mild conditions.
- PEG4 spacer increases solubility and reduces steric hindrance.
- High reported purity suitable for research use.
- Available in small laboratory quantities for convenient use.
Medchemexpress LLC Amine-PEG-CH2COOH (MW 2000) | 139729-28-5 | 95.0% | 50 MG
Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker primarily used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It is designed for research purposes and is not intended for patient use.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
![eMolecules Broadpharm / DBCO-PEG8-Maleimide / 25mg / 686678581 / BP-25729 / / / [null] / 850.963 / C44H58N4O13](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502499483.JPG-250.jpg)
eMolecules Broadpharm / DBCO-PEG8-Maleimide / 25mg / 686678581 / BP-25729 / / / [null] / 850.963 / C44H58N4O13
Broadpharm / DBCO-PEG8-Maleimide / 25mg / 686678581 / BP-25729 / / / [null] / 850.963 / C44H58N4O13
Cayman Chemical dPE-PEG 2000-Mnose 5mg
An antagonist of CXCR4 (IC50s 0.02-0.13 Ug/ml) selective for CXCR4 over CXCR1-3 and CXCR5-9 (IC50s 25 Ug/ml) decreases infectious virus content in the supernatant of Jurkat cells chronically infected with HIV-1(IIIB) (EC50 ~0.02 Ug/ml) mobilizes murine and human hematopoietic stem and murine long-term repopulating cells for transplantation increases T cell trafficking in mouse blood spleen and central nervous system decreases the number of 4T1 murine mammary carcinoma cells in the lung in a mouse model of lung metastasis at 1.25 mg/kg twice per day
Medchemexpress LLC DSPE-PEG-FITC | 1000788-53-3 | 100 MG
DSPE-PEG-FITC (MW 10000) is a fluorescein-labeled DSPE-PEG amphiphilic conjugate (average molecular weight 10,000 Da) that forms micelles in aqueous solution. It is commonly used to prepare fluorescent liposomes and nanoparticles for research in drug delivery and imaging, and is supplied for research use only.
- Provides fluorescein labeling for visualization in fluorescence assays.
- Forms micelles and incorporates into liposome bilayers for nanoparticle formulation.
- Average molecular weight supports steric stabilization and extended circulation.
- Available in laboratory-friendly pack sizes including 100 mg.
- Supplied with supporting documents such as COA and SDS for quality control.
eMolecules Fmoc-Lys (biotin-PEG12)-OH | | | 500mg
Broadpharm | Fmoc-Lys (biotin-PEG12)-OH | 500mg | 272383804 | BP-22614 | 95.000 | | | 1194.440 | C58H91N5O19S
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Medchemexpress LLC Fmoc-NH-PEG4-CH2COOH | 437655-95-3 | 99.1% | 473.52 | C25H31NO8 | 250 MG
Fmoc-NH-PEG4-CH2COOH is an Fmoc-protected PEG4 linker with a terminal carboxylic acid. It serves as a cleavable spacer in antibody-drug conjugate and PROTAC assembly, and as a pegylated spacer for peptide conjugation to increase solubility and provide a site for functionalization.
- Fmoc-protected amine with terminal carboxylic acid
- Peg4 spacer increases solubility and flexibility
- Suitable for antibody-drug conjugate (ADC), proteolysis-targeting chimera (PROTAC), and peptide conjugation chemistries
- Available in small-scale quantities for synthesis and method development
- Store at low temperature in a sealed container to minimize moisture exposure
Medchemexpress LLC TCO-PEG3-Biotin | 570.74 | C27H46N4O7S | 5 MG
TCO-PEG3-Biotin is a cleavable three-unit polyethylene glycol (PEG) linker bearing a trans-cyclooctene (TCO) group and a biotin tag used for click chemistry and antibody-drug conjugate (ADC) synthesis. It enables rapid inverse electron-demand Diels-Alder (iEDDA) ligation with tetrazine partners and supports affinity capture or detection via the biotin handle.
- Cleavable 3-unit PEG linker for bioconjugation.
- Trans-cyclooctene (TCO) group enables inverse electron-demand Diels-Alder (iEDDA) click reactions.
- Biotin tag facilitates affinity capture and detection workflows.
- Molecular weight 570.74 and formula C27H46N4O7S support stoichiometric conjugation planning.
- Available in small milligram quantities suitable for conjugation development and testing.
eMolecules Benzyl-PEG5-CH2CO2tBu | 1807503-89-4 | MFCD28122960 | 1g
Broadpharm | Benzyl-PEG5-CH2CO2tBu | 1g | 254745489 | BP-22255 | 98.000 | 1807503-89-4 | MFCD28122960 | 398.496 | C21H34O7
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Medchemexpress LLC Propargyl-PEG4-NHS ester | 1428629-70-2 | 97.0% | 357.36 g·mol⁻¹ | C16H23NO8 | 100 MG
Propargyl-PEG4-NHS ester is a PEG4 linker with a terminal propargyl (alkyne) group and an N-hydroxysuccinimide (NHS) ester, designed for bioconjugation via amine coupling and click chemistry.
- Noncleavable four-unit PEG linker for spacer and solubility
- Terminal propargyl group enables copper-catalyzed azide-alkyne cycloaddition
- NHS ester provides rapid and efficient coupling to primary amines
- High purity suitable for research applications
- Molecular weight approximately 357.36 g·mol⁻¹
- Available in small research-scale package sizes
Medchemexpress LLC Benzyl-PEG4-Ots 500mg
Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs
Medchemexpress LLC Mal-PEG4-NHS ester | 1325208-25-0 | 99.4% | 442.42 | C19H26N2O10 | 250 MG
Mal-PEG4-NHS ester is a PEG-based crosslinker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester separated by a four-unit polyethylene glycol spacer. It is used for conjugation of thiol-containing molecules to primary amines for bioconjugation and nanoparticle functionalization in research applications.
- Non-cleavable maleimide-NHS linker for thiol-to-amine conjugation.
- Four-unit polyethylene glycol spacer increases solubility.
- High purity (99.4% by HPLC).
- Molecular weight 442.42, formula C19H26N2O10.
- Available in small lab pack sizes, including 250 MG.
- For research use only; not for therapeutic use.