Protein Modification Reagents
Broadpharm Sulfo DBCO-PEG4-Maleimide | 2055198-07-5 | MFCD30458040 | 25mg
Sulfo DBCO-PEG4-Maleimide | Putity: 90% | MW: 825.9 | 2055198-07-5 | MFCD30458040 | 25mg
Medchemexpress LLC P5(PEG24)-VC-PAB-Exatecan | 2928571-43-9 | 99.7% | 2105.28 | 1 MG
P5(PEG24)-VC-PAB-Exatecan (LP5) is a drug-linker conjugate composed of a potent DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker P5(PEG24)-VC-PAB to make antibody agent conjugate (ADC). It can be used for tumor research.
- Drug-linker conjugate for ADC
- Contains a potent DNA Topoisomerase I inhibitor (Exatecan)
- Can be used for the research of tumor
Medchemexpress LLC Bis-PEG4-NHS ester | 1314378-11-4 | 97.0% | 488.44 g/mol | C20H28N2O12 | 100 MG
Bis-PEG4-NHS ester is a non-cleavable polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester reactive groups, designed for bioconjugation and antibody-drug conjugate (ADC) linker chemistry. It couples to primary amines to form stable amide bonds and is supplied as a solid with supporting analytical and handling documentation.
- Non-cleavable 4-unit PEG linker suitable for ADC and bioconjugation
- NHS ester functional groups for efficient coupling to primary amines
- High purity, suitable for research applications
- Solid form, white to off-white appearance
- Stable when stored as powder at -20°C
- Available in multiple pack sizes to support different scales of work
eMolecules 2055041-41-1 | HN-(PEG4-CH2CH2COOtBu)2 | Acrotein ChemBio Inc. | MFCD29912666 | 625.797 | C30H59NO12 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 0.5g | 518518368
HN-(PEG4-CH2CH2COOtBu)2 | Acrotein ChemBio Inc. | 2055041-41-1 | MFCD29912666 | 625.797 | C30H59NO12 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCNCCOCCOCCOCCOCCC(=O)OC(C)(C)C | 0.5g | 518518368
Medchemexpress LLC Biotin-PEG4-PFP ester | 1334172-58-5 | MFCD13184979 | 96.2% | 657.65 | C27H36F5N3O8S | 50 MG
Biotin-PEG4-PFP ester is an activated biotin linker containing a four-unit polyethylene glycol (PEG4) spacer and a pentafluorophenyl (PFP) ester leaving group. It is designed for efficient amine coupling and biotin tagging in bioconjugation workflows such as ADC and PROTAC synthesis.
- Cleavable PEG4 spacer provides flexibility and solubility
- PFP activated ester enables rapid coupling to primary amines
- Biotin tag allows affinity capture and detection
- Suitable for antibody-drug conjugate and probe labeling workflows
- Stable as a powder at -20°C for extended storage
eMolecules 868594-52-9 | Fmoc-nh-peg8-ch2cooh | Combi-Blocks | MFCD27635163 | 649.734 | C33H47NO12 | 95.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 457919886
Fmoc-nh-peg8-ch2cooh | Combi-Blocks | 868594-52-9 | MFCD27635163 | 649.734 | C33H47NO12 | 95.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 457919886
Medchemexpress LLC Nhpi-peg4-c2-nhs ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 g/mol | C23H28N2O11 | 1 G
NHPI-PEG4-C2-NHS ester is a PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is supplied for research use and has a molecular weight of 508.48 g/mol and formula C23H28N2O11. Store the pure material at -20°C; observe low-temperature storage for solutions.
Medchemexpress LLC Alkyne-PEG2-iodide | 1234387-33-7 | C₇H₁₁IO₂ | 250 MG
Alkyne-PEG2-iodide is a click chemistry reagent designed with terminal alkyne and alkyl iodide groups. It functions as an ADC linker, suitable for various research applications.
- Click chemistry reagent
- Features terminal alkyne and alkyl iodide groups
- Acts as an ADC linker
- Related to antibody-drug conjugate/ADC applications
- For research use only
Cayman Chemical mal-PEG2-AZD 50mg
A bioconjugation linker; has been used in the development of protein- and peptidomimetic-antibody conjugates
Medchemexpress LLC N-succinimidyl 4,7,10,13-tetraoxatetradecanoate | 622405-78-1 | MFCD11041112 | 95.0% | 333.33 g/mol | C14H23NO8 | 5G
m-PEG4-NHS ester is a monomethyl-capped polyethylene glycol (PEG4) reagent terminating in an N-hydroxysuccinimide (NHS) ester. It is used as an amine-reactive PEGylation linker and as a spacer in PROTAC and bioconjugation chemistry, enabling attachment of a PEG4 spacer to primary amines on small molecules, peptides, or proteins. CAS 622405-78-1; molecular weight 333.33 g/mol.
Medchemexpress LLC 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo | 1263045-16-4 | 99.8% | 500 MG
Mal-amido-PEG4-acid is an off-white to yellow solid with a molecular formula of C18H28N2O9 and a molecular weight of 416.42. It exhibits a high purity of 99.76% as determined by HPLC analysis, and its 1H NMR and LCMS spectra are consistent with the chemical structure.
- Off-white to yellow solid appearance
- Molecular formula C18H28N2O9
- Molecular weight 416.42
- Purity of 99.76% (HPLC)
- NMR and LCMS data consistent with structure
- Store at -20°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
![eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502508684.JPG-250.jpg)
eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
Medchemexpress LLC PROTAC STING degrader-3 | 3109967-69-0 | 98.0% | 752.73 | 1 MG
PROTAC STING degrader-3 is a STING PROTAC degrader that induces STING degradation via the ubiquitin-proteoteasome pathway. It exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-κB signaling and has renal protective effects, making it useful in the study of acute kidney injury (AKI).
- STING ligand
- Cereblon ligand
- Linker
eMolecules 557756-85-1 | Fmoc-NH-PEG4-CH2CH2COOH | AbaChemScene | MFCD06656472 | 487.549 | C26H33NO8 | 96.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 391087612
Fmoc-NH-PEG4-CH2CH2COOH | AbaChemScene | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 96.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 391087612
eMolecules 93206-09-8 | Benzyl-PEG2-CH2CO2H | Broadpharm | MFCD16294180 | 210.229 | C11H14O4 | 98.000 | OC(=O)COCCOCc1ccccc1 | 1g | 247403023
Benzyl-PEG2-CH2CO2H | Broadpharm | 93206-09-8 | MFCD16294180 | 210.229 | C11H14O4 | 98.000 | OC(=O)COCCOCc1ccccc1 | 1g | 247403023